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背景:功能性便秘对小儿的身心健康、社会心理发育和远期生活质量均有很大影响。目前国内尚无儿童功能性便秘的确切定义,无明确分型,亦无统一诊断标准和系统的治疗方案。而胃肠传输时间测定是客观了解胃肠转运功能的动力学检查方法之一,对胃肠道动力异常的诊断、病因研究和疗效评价具有重要意义,是目前诊断慢传输型便秘的惟一无创手段。目的:分析功能性便秘患儿和正常儿童胃肠传输时间区别,了解胃肠传输时间测定在评估全胃肠及各段动力的意义。设计:以患儿、正常儿童为研究对象,病例-对照,观察对比研究。单位:武警部队广东总队医院儿科。对象:研究对象为2002-08广州市某幼儿园和某小学健康儿童共68例及2002-03/2003-01在武警部队广东总队医院儿科门诊确诊或住院的功能性便秘患儿28例。方法:通过口服不透X线标志物,用X线拍片法分别于12,24和48h摄腹部平片,测定28例功能性便秘患儿和68例正常儿童全胃肠传输时间、口-盲时间和结肠传输时间。主要观察指标:功能性便秘患儿与正常儿童全胃肠传输时间、口-盲时间、结肠传输时间以及右半结肠传输时间、左半结肠传输时间、直肠乙状结肠传输时间比较。结果:正常儿童及功能性便秘患儿的50%全胃肠传输时间犤(23.6±1.6),(80.4±2.1)h犦,口-盲时间犤(9.9±1.4),(20.7±
Background: Functional constipation has great influence on children’s physical and mental health, social and psychological development and long-term quality of life. At present there is no exact definition of functional constipation in children, there is no clear type, there is no uniform diagnostic criteria and systematic treatment. The determination of gastrointestinal transit time is one of the kinetic methods to objectively understand the function of gastrointestinal transit. It is of great importance to the diagnosis of gastrointestinal motility abnormalities, etiology and efficacy evaluation, and is the only noninvasive means to diagnose slow transit constipation . OBJECTIVE: To analyze the difference of gastrointestinal transit time between functional constipation children and normal children, and to understand the significance of the determination of gastrointestinal transit time in assessing the motility of the whole intestine and the segments. Design: In children, normal children as the research object, case-control, observe the comparative study. Unit: Armed Police Corps Hospital of Guangdong Pediatrics. PARTICIPANTS: A total of 28 children with functional constipation diagnosed or hospitalized in pediatric outpatient department of Guangdong Armed Police Corps from February 2002 to January 2003 were enrolled. Methods: Totally 28 patients with functional constipation and 68 normal children were examined for total gastrointestinal transit time and oral-blind by X-ray film radiography at 12, 24 and 48 hours respectively. Time and colon transit time. MAIN OUTCOME MEASURES: Total intestine transit time, mouth-blind time, colon transit time and right colon transit time, left colon transit time, and rectal sigmoid transit time in children with functional constipation were compared with those in normal children. Results: The 50% total gastrointestinal transit time in children with normal constipation and functional constipation was (23.6 ± 1.6), (80.4 ± 2.1) h, (9.9 ± 1.4), (20.7 ±