This paper reports geochemical and Pb-Sr-Nd isotopic compositions of the Indosinian Yangba (215 Ma),Nanyili (225 Ma) and Mopi granitoids from the Bikou block of the northwestern margin of the Yangtze plate. These granitoids are enriched in Al (Al2O3:14.56%―16.48%) and Sr (352 μg/g―1047 μg/g),and depleted in Y (<16 μg/g) and HREE (e.g. Yb<1.61 μg/g),resulting in high Sr/Y (36.3―150) and (La/Yb)N (7.8―36.3) ratios and strongly fractionationed REE patterns. The Indosinian granotoids show initial Sr isotopic ratios (ISr) from 0.70419 to 70752,εNd(t) values from-3.1 to -8.5,and initial Pb isotopic ratios 206Pb/204Pb=17.891-18.250,207Pb/204Pb=15.494-15.575,and 208Pb/204Pb=37.788-38.335. Their geochemi-cal signatures indicate that the granitoids are adakitic. However,they are distinct from some adakites,generated by partial melting of subducted oceanic slab and/or underplated basaltic lower crust,be-cause they have high K (K2O: 1.49%―3.84%) and evolved Nd isotopic compositions,with older Nd iso-topic model ages (TDM=1.06―1.83 Ga). Geochemical and Sr-Nd isotopic compositions suggest that the magmas of the Insoninian adakitic rocks in the Bikou block were derived from partial melting of thick-ened basaltic lower crust. Combined with regional analyses,a lithospheric delamination model after collision between the North China and South China plates can account for the Indosinian adakitic magma generation. On the other hand,based on the Pb-Sr-Nd isotopic probing to the magma sources of the adakitic rocks,it is suggested that there is an unexposed continent-type basement under the exposed Bikou Group volcanic rocks. This can constrain on the Bikou Group volcanic rocks not to be MORB-or OIB-type. This paper reports geochemical and Pb-Sr-Nd isotopic compositions of the Indosinian Yangba (215 Ma), Nanyili (225 Ma) and Mopi granitoids from the Bikou block of the northwestern margin of the Yangtze plate. These granitoids are enriched in Al : 14.56% -16.48%) and Sr (352 μg / g-1047 μg / g), and depleted in Y (<16 μg / g) and HREE (eg Yb <1.61 μg / g) The Indosinian granotoids show initial Sr isotopic ratios (ISr) from 0.70419 to 70752, εNd (t) values ​​from-3.1 to - (36.3-150) and (La / Yb) 8.5, and initial Pb isotopic ratios 206Pb / 204Pb = 17.891-18.250, 207Pb / 204Pb = 15.494-15.575, and 208Pb / 204Pb = 37.788-38.335. Their geochemi-cal signatures indicate that the granitoids are adakitic. However, they are distinct from some adakites, generated by partial melting of subducted oceanic slab and / or underplated basaltic lower crust, be-cause they have high K (K2O: 1.49% -3.84%) and evolved Nd isotopic compositions, with older Nd iso-topic models ages (TDM = 1.06-1.83 Ga). Geochemical and Sr-Nd isotopic compositions suggest that the magmas of the Insoninian adakitic rocks in the Bikou block were derived from partial melting of thick-ened basaltic lower crust. Combined with regional analyzes, a lithospheric delamination model after collision between the North China and South China plates can account for the Indosinian adakitic magma generation. On the other hand, based on the Pb-Sr-Nd isotopic probing to the magma sources of the adakitic rocks, it is suggested that there is an unexposed continent-type basement under the exposed Bikou Group volcanic rocks. This can constrain on the Bikou Group volcanic rocks not to be MORB-or OIB-type.