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目的 :探索微生态制剂在小儿腹泻中的临床疗效及对患儿肠道菌群的影响。方法 :采集我院2016年2月至2016年9月儿科收治的46例小儿腹泻患儿作为观察对象,随机将其分为对比组和试验组,每组各23例,对比组采用思密达治疗,试验组采用微生态制剂治疗,对比两组患儿的治疗效果及肠道菌群的变化情况。结果 :试验组治疗总有效率91.3%显著高对比组治疗的总有效率73.91%,两组对比差异有统计学意义(P<0.05);试验组的乳杆菌属及肠球菌属数量均明显高于对比组,两组对比差异有统计学意义(P<0.05);试验组的酵母样真菌数量明显低于对比组,两组对比差异有统计学意义(P<0.05)。结论 :微生态制剂在治疗小儿腹泻上有很好的疗效,平衡了患儿的肠道菌群,改善了患儿症状及体征,是治疗小儿腹泻较为理想的方法。
Objective: To explore the clinical efficacy of probiotics in children with diarrhea and its effect on the intestinal microflora in children. Methods: Forty-six children with pediatric diarrhea admitted to our hospital from February 2016 to September 2016 were randomly divided into control group and experimental group, with 23 cases in each group. The patients in control group were treated with Smectite Treatment, the experimental group treated with probiotics, compared the treatment effect of two groups of children and changes in intestinal flora. Results: The total effective rate of experimental group was 91.3%, which was significantly higher than that of the control group (73.91%), the difference was statistically significant (P <0.05). The numbers of Lactobacillus and Enterococcus in the experimental group were significantly higher The difference between the two groups was statistically significant (P <0.05). The number of yeast-like fungi in the experimental group was significantly lower than that in the control group (P <0.05). Conclusion: The probiotics have a good curative effect in the treatment of infantile diarrhea, which balance the gut flora in children and improve the symptoms and signs in children. It is an ideal method to treat infantile diarrhea.