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目的:探讨急诊PCI对急性ST段抬高型心肌梗死患者左心室功能疗效影响。方法:选择我院2009年9月~2011年9月急性ST段抬高型心肌梗死患者70例,上述患者分为2组,观察组和对照组。对照组实施择期PCI。对照组实施择期PCI,患者在发病12小时内不同意实施急诊PCI,选择溶栓治疗或者保守治疗,或者由于其他原因而失去急诊PCI时机。患者在发病后7~14天内根据冠脉造影并对梗死相关动脉和严重狭窄的非梗死相关动脉实施PCI。观察组患者实施急诊PCI,患者在发病12小时内直接实施PCI。采用彩色多普勒超声检查观察2组患者术后7天和术后6个月左室射血分数改变情况;采用6分钟步行试验观察2组术后6个月心功能情况。结果:观察组术后7天和术后6个月左室射血分数分别与对照组比较,差异有统计学意义(P<0.05);观察组术后6个月6分钟步行试验大于550m所占比例显著高于对照组,差异有统计学意义(P<0.05)。结论:急诊PCI能够显著改善急性ST段抬高型心肌梗死左心室功能,疗效显著,值得借鉴。
Objective: To investigate the effect of emergency PCI on left ventricular function in patients with acute ST-segment elevation myocardial infarction. Methods: Seventy patients with acute ST-elevation myocardial infarction from September 2009 to September 2011 in our hospital were divided into two groups: observation group and control group. The control group underwent elective PCI. Patients in the control group underwent elective PCI. Patients did not agree to implement emergency PCI within 12 hours of onset, or thrombolytic therapy or conservative treatment, or missed emergency PCI for other reasons. Patients underwent coronary angiography 7 to 14 days after onset and performed PCI on infarct-related arteries and severely stenosed non-infarcted arteries. Patients in the observation group underwent emergency PCI, and patients underwent PCI directly within 12 hours of onset. Color Doppler echocardiography was used to observe the changes of left ventricular ejection fraction (LVEF) at 7 days and 6 months after operation in both groups. The 6-minute walk test was used to observe the cardiac function of the two groups at 6 months after operation. Results: The left ventricular ejection fraction at 7 days and 6 months after operation in the observation group was significantly higher than that in the control group (P <0.05). The 6-minute walking test at 6 months after operation in the observation group was more than 550 meters The proportion was significantly higher than the control group, the difference was statistically significant (P <0.05). Conclusion: Emergency PCI can significantly improve left ventricular function in patients with acute ST-segment elevation myocardial infarction. The results are significant and worth learning from.