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人体微生物组计划开展近10年来,大量的研究显示人体微生物通过各种方式深刻地影响着人体健康。人体肠道内丰富多样的病毒构成了肠道病毒组,是人体微生物组的重要组成部分,和人体健康密切相关。本文综述了近些年国际上人体肠道病毒组研究的最新进展,分别从人体肠道病毒组的组成特征、肠道病毒组-细菌组-人体间的相互作用及其对人体健康的影响、病毒组研究的技术策略及挑战等方面进行了论述,探讨了肠道病毒组在人体疾病预防和治疗领域应用的可行性。
Human Microbiology Group is planning to carry out the past 10 years, a large number of studies have shown that human micro-organisms through a variety of ways profound impact on human health. The abundant and diverse virus in the human intestine constitutes the enterovirus group, which is an important part of the human microbiome and is closely related to human health. This review summarizes the recent progress in the research on human intestinal enterovirus in recent years. It mainly analyzes the compositional characteristics of human enteroviruses, the interaction between enterovirus and bacterial groups - human and their effects on human health, The technical strategies and challenges of virus group research were discussed, and the feasibility of application of enterovirus in human disease prevention and treatment was discussed.