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目的：探讨研究严重抑郁症应用无抽搐电休克进行治疗，分析其对认知功能的影响及临床护理观察。方法：择取我院于2012年7月-2013年7月接收确诊属严重抑郁症的86例患者，均使用双侧电极的无抽搐电休克予以治疗。分别在治疗前；急性期治疗结束1天；维持期治疗的6周末；维持期治疗的16周末应用汉密尔顿抑郁表（简称 HAMD）与韦氏记忆量表（简称WMS）进行评定。结果：本组86例严重抑郁症患者采用无抽搐电休进行治疗的有效率是79．07％，临床症状得到明显好转，其差异P＜0．0．5，说明有统计学意义。结论：严重抑郁症采用无抽搐电休克予以治疗，能够显著改善患者的临床症状。“,”Objective :to study the research application without major depression tic electric shock treatment ,to analyze its influence on cognitive function and clinical nursing observation .Methods :will pick the hospital in July 2012 -July 2013 receive diagnosis of 86 patients of severe depression , using the both sides of the electrode without seizure electroconvulsive therapy .Before treatment respectively ;The end of therapy on the acute phase 1 day ;Maintenance phase treatment 6 weekend ;Maintenance phase treatment of 16 weekend using the Hamilton depression (HAMD) and wechsler memory scale (WMS) to assess .Conclusion:treatment with severe depression without seizure electric shock ,can significantly improve the clinical symptoms of patients .