大量事实均表明前列腺癌的发生、发展和雄激素有着密切依赖的关系。因此,以外科手术或者药物为手段的雄激素撤退治疗成为前列腺癌特别是晚期前列腺癌的标准治疗方法之一。尽管治疗的最初阶段有良好的反应,但超过80%的患者将最终转化为激素非依赖性(激素拮抗的前列腺癌),导致治 A large number of facts show that the occurrence and development of prostate cancer and androgen have a close relationship. Therefore, the treatment of androgen withdrawal by means of surgery or medicine becomes one of the standard treatment methods for prostate cancer, especially advanced prostate cancer. Despite good response during the initial stages of treatment, over 80% of patients will eventually turn hormone-independent (hormone-antagonist prostate cancer) into treatment