女性进入绝经期后由于体内雌、孕激素水平明显下降,各种退化性疾病如骨质疏松、骨折、心脑血管疾病等会伴随发生,严重影响女性的身体健康和生活质量。目前,激素替代疗法(HRT)因能够有效缓解绝经期症状、延缓骨质疏松发生,降低骨折发生率及预防心血管疾病发生等,在临床上得到广 After entering the menopause period, the women’s estrogen and progesterone levels decline significantly. Various degenerative diseases such as osteoporosis, fractures and cardiovascular and cerebrovascular diseases are accompanied with serious impact on women’s health and quality of life. At present, hormone replacement therapy (HRT) is clinically widely available because it can effectively relieve the symptoms of menopause, delay the occurrence of osteoporosis, reduce the incidence of fractures and prevent the occurrence of cardiovascular diseases