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目的:了解脑梗死并发肺部感染病原菌与抗菌药物使用间的关系。方法:回顾性分析33例脑梗死并发肺部感染病原菌及抗菌药物治疗情况。结果:患者以男性和老年人居多;革兰阴性菌感染占优势(67.9%);产超广谱β-内酰胺酶的肺炎克雷伯菌和大肠埃希菌的检出率为42.9%;铜绿假单胞菌对常用的多种抗菌药物耐药;抗菌药物应用率最高的依次为头孢哌酮/舒巴坦、左氧氟沙星和莫西沙星。结论:分析感染病原菌与抗菌药物应用的关系,可为临床合理用药提供参考。
Objective: To understand the relationship between pathogen of pulmonary infection and antibiotic use in patients with cerebral infarction. Methods: A retrospective analysis of 33 cases of cerebral infarction complicated by pulmonary infection and antimicrobial agents. Results: The majority of patients were male and the elderly. Gram-negative bacteria was predominant (67.9%). The detection rate of Klebsiella pneumoniae and Escherichia coli with extended-spectrum β-lactamase was 42.9% Pseudomonas aeruginosa commonly used in a variety of antimicrobial resistance; antibacterial drug application rates were cefoperazone / sulbactam, levofloxacin and moxifloxacin. Conclusion: The analysis of the relationship between the infection of pathogens and the application of antimicrobial agents may provide a reference for clinical rational drug use.