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了解影响小儿急性肾功能衰竭（ARF）预后的临床相关因素。方法回顾性总结了1988～1997年住院的ARF患儿39例。结果1．小儿ARF近期死亡率17．9％，总死亡率23．1％，预后不良35．9％。2．年龄越小死亡率越高，婴幼儿ARF死亡率在50％以上；药物性肾衰预后差。Scr与预后明显相关；而病程中合并严重感染、高钠血症、血K+＞6．0mmol／L死亡率高；腹膜透析病人死亡率也明显高于血液透析者。3．发展为慢性肾衰主要取决于原发病类型，而与年龄、Scr、并发症等无关。结论小儿ARF预后差。影响预后的因素包括发病年龄、原发疾病、肾功能减退程度、并发症及治疗等。
Understand the clinical factors affecting the prognosis of children with acute renal failure (ARF). Methods A retrospective review of 39 hospitalized children with ARF from 1988 to 1997. Results 1. Recent pediatric ARF mortality rate of 17.9%, the total mortality rate of 23.1%, poor prognosis 35.9%. 2. The younger the mortality rate is higher, ARF mortality in infants and children in more than 50%; poor prognosis of drug-induced renal failure. Scr and prognosis were significantly related to the duration of severe infection, hypernatremia, blood K +> 6.0mmol / L high mortality rate; peritoneal dialysis patients mortality was significantly higher than hemodialysis patients. 3. The development of chronic renal failure mainly depends on the type of primary disease, but not with age, Scr, complications and so on. Conclusion The prognosis of children with ARF is poor. Factors that affect the prognosis include age of onset, primary disease, degree of renal dysfunction, complications and treatment.