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作者报告1例放疗治疗重症肌无力病人,33岁,因重症肌无力症状(Ossermann分期Ⅲ)。新斯的明试验阳性,1984年行胸腺摘除术,术后诊断为良性淋巴上皮细胞性胸腺瘤。后病情继续加重需加压辅助呼吸。4个月后作第一次全淋巴系统照射(~(60)钻),依次照射颈下淋巴结、双侧锁骨上区和纵隔(中心平面剂量为20Gy,每周四次,每次25Gy)、腹主动脉旁淋巴结和脾(未照髂淋巴链和腹股沟区以保护卵巢功能)。照射中肌无力症开始好转,后中止辅助呼吸,减少皮质激素剂量症状持续
The authors report a case of radiation therapy for myasthenia gravis patients, 33 years old, due to symptoms of myasthenia gravis (Ossermann staging III). Neostigma test positive, thymectomy in 1984, postoperative diagnosis of benign lymphoblastic cell thymoma. After the condition continues to increase need to assist the breathing pressure. After 4 months, the first full-lymphatic system irradiation (~60) was performed, followed by irradiation of the sub-cervical lymph nodes, bilateral supraclavicular region and mediastinum (central plane dose of 20 Gy, four times per week, 25 Gy each time). Abdominal aortic lymph nodes and spleen (not protected lymph nodes and groin area to protect ovarian function). Myasthenia gravis began to improve during irradiation, after which secondary breathing was stopped, and the corticosteroid dose continued to decrease.