蛋白聚糖(PG)是造血微环境中重要的大分子物质,能与造血因子等特异性地结合,在造血干细胞粘附基质细胞及造血调控中有重要作用。对PG的深入研究,有助于认识在生理及病理情况下的造血调控,从而能更有效地治疗造血失控引起的血液疾病。 Proteoglycan (PG), an important macromolecular substance in the hematopoietic microenvironment, can specifically bind to hematopoietic factors and plays an important role in the regulation of hematopoietic stem cell adhesion and proliferation. In-depth study of PG helps to understand the regulation of hematopoiesis in physiological and pathological conditions, so that hematological disorders caused by hematopoietic disorders can be more effectively treated.