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大鼠吸入过滤或未过滤柴油机排出物，每天染毒８小时，分别染毒２天、５天、８天。肺灌洗液分析发现：染毒两天组肺巨噬细胞数（ＰＭＮ）明显降低，乳酸脱氢酶（ＬＤＨ）活性和丙二醛（ＭＤＡ）含量增高，酸性磷酸酶（ＡＣＰ）活性和唾液酸（ＮＡ）含量升高在染毒８天组观察到。动物吸入过滤后柴油机排出物，肺巨噬细胞数降低较缓慢，其他指标地高也不明显。结果显示：吸入柴油机排出物能引起机体肺组织损伤，大鼠吸入经过滤的柴油机排出物后，肺损伤程度有所降低。
Rat inhalation or unfiltered diesel emissions, 8 hours a day, were exposed to 2 days, 5 days, 8 days. Pulmonary lavage fluid analysis showed that the number of pulmonary macrophages (PMN), lactate dehydrogenase (LDH) activity and the content of malondialdehyde (MDA) were significantly increased, the activities of ACP and saliva Elevated acid (NA) levels were observed on the 8-day exposure. After inhalation and filtration, the diesel engine effluent and the number of pulmonary macrophages decreased more slowly, and the height of other indexes was not obvious either. The results showed that inhalation of diesel emissions caused lung injury in the body, and decreased lung injury after rats inhaled filtered diesel emissions.