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从1991年10月-1993年6月对45岁以上男性,44例正常人和87例肺癌患者血中8种内分泌激素进行测定,肺癌病人治疗前Cort、β-HC、Gluc和PRL明显高于正常人群。87例肺癌治疗前按不同病理比较,腺癌β-HCG明显高于其它病理类型,鳞癌PRL高于其它,小细胞未分化Gast高于其它。43例肺癌治疗后,TSH、PRL、Cort和Glue都明显降低,而GH则升高,11例治疗后肿瘤复又增大或远处转移的肺癌患者,再次测定激素水平表明,PRL、Cort和Glue复又升高。这些结果说明部分内分泌激素,可用于男性肺癌的早期诊断或鉴别诊断,有些激素可作为肺癌病理分类的参考。
From October 1991 to June 1993, eight endocrine hormones in the blood of men over 45 years of age, 44 normal controls, and 87 patients with lung cancer were measured. Before the treatment of lung cancer patients, Cort, β-HC, Gluc, and PRL were significantly higher than those before treatment. Normal population. Before the treatment of 87 patients with lung cancer, according to different pathological features, adenocarcinoma β-HCG was significantly higher than other pathological types. The squamous cell carcinoma PRL was higher than other, small cell undifferentiated Gast was higher than other. After treatment of 43 patients with lung cancer, TSH, PRL, Cort, and Glue were all significantly lower, while GH was elevated. In 11 patients with lung cancer after treatment with increased tumor complex or distant metastases, the hormone levels were measured again to show that PRL, Cort, and Glue rose again. These results indicate that some endocrine hormones can be used for the early diagnosis or differential diagnosis of male lung cancer, and some hormones can be used as a reference for lung cancer pathological classification.