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目的探讨肝动脉化疗栓塞联合全身化疗治疗肝转移性肿瘤的疗效。方法回顾分析2004年1月至2009年12月我院6年来收治肝脏转移性肿瘤58例,原发病灶来源:大肠癌28例,胃癌18例,食管癌8例,小肠癌4例,经皮股动脉穿刺肝动脉化疗栓塞(TAE),共118次治疗。联合全身化疗方案:大肠癌、小肠癌使用奥沙利铂,胃癌、食管癌使用紫杉醇。结果治疗后总有效率48.2%及半年、一年、二年的生存率分别为89.6%、55,2%、31.0%。结论肝动脉化疗栓塞联合全身化疗治疗是治疗肝脏转移性肿瘤重要手段,能达到病灶缩小,缓解症状,延长寿命,提高生活质量。
Objective To investigate the efficacy of transcatheter arterial chemoembolization combined with systemic chemotherapy in the treatment of liver metastatic tumors. Methods From January 2004 to December 2009, 58 cases of liver metastases from January 2004 to December 2009 in our hospital were retrospectively analyzed. The origin of the primary tumors were: 28 cases of colorectal cancer, 18 cases of gastric cancer, 8 cases of esophageal cancer and 4 cases of small intestine cancer. Femoral artery puncture hepatic artery chemoembolization (TAE), a total of 118 treatment. Combined systemic chemotherapy: Colorectal cancer, small intestine cancer using oxaliplatin, gastric cancer, esophageal cancer using paclitaxel. Results After treatment, the total effective rate was 48.2% and the half-year, one-year and two-year survival rates were 89.6%, 55.2% and 31.0% respectively. Conclusions Hepatic arterial chemoembolization combined with systemic chemotherapy is an important method for the treatment of metastatic liver tumors. It can reduce the lesion, relieve the symptoms, prolong the life span and improve the quality of life.