在早期乳腺癌的各种预后性征候中,最重要的是腋淋巴结入侵。根据以往的经验,淋巴结阴性的患者,10年后的存活率大约70％,30％的患者可能复发或死亡;淋巴结阳性患者的复发率占30～60％,它取决于阳性淋巴结的数量和其它的预后因素,诸如雌激素受体的存在。淋巴结阴性患者:对一组90例淋巴结阴性和雌激素受体阴性的患者,比较了包括环磷酰胺、甲氨喋呤和氟脲嘧啶的细胞毒药物化疗方 Among the various prognostic signs of early breast cancer, the most important is the invasion of axillary lymph nodes. According to past experience, lymph node-negative patients have a survival rate of approximately 70% after 10 years, and 30% of patients may relapse or die; the recurrence rate of lymph node positive patients accounts for 30 to 60%, depending on the number of positive lymph nodes and others. The prognostic factors such as the presence of estrogen receptors. Patients with lymph node negative: For a group of 90 patients with negative lymph node and negative estrogen receptors, cytotoxic drugs including cyclophosphamide, methotrexate and fluorouracil were compared