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目的探讨体外高频热疗机在晚期食管癌治疗中的临床疗效。方法将我院收治的23例晚期食管癌患者随机分为热疗联合放疗组(治疗组,12例)与单纯放疗组(对照组,11例)。治疗组给予外照射DT 40 Gy,2 Gy/次,5次/周,腔内加温1~2次/周,60 m in/次,静脉化疗1次/周;对照组采用单纯放化疗,外照射DT 40 Gy,2 Gy次/,5次/周。比较两组的近远期疗效。结果两组完全缓解率、局部控制率、5年和7年生存率比较差异均有统计学意义(P<0.05),两组的1年和3年生存率比较差异无统计学意义(P>0.05)。结论体外高频热疗治疗晚期食管癌远期疗效满意,治疗操作简单、损伤小、防护安全,能改善患者生活质量。
Objective To investigate the clinical efficacy of extracorporeal high frequency hyperthermia in the treatment of advanced esophageal cancer. Methods Twenty-three patients with advanced esophageal cancer admitted to our hospital were randomly divided into two groups: hyperthermia combined with radiotherapy (treatment group, 12 cases) and radiotherapy alone group (control group, 11 cases). The patients in the treatment group were treated with external radiotherapy (DT 40 Gy, 2 Gy / time, 5 times / week, intraluminal heating 1-2 times / week, 60 mins / time and intravenous chemotherapy once / External radiation DT 40 Gy, 2 Gy times /, 5 times / week. Short-term efficacy of the two groups were compared. Results The complete remission rate, local control rate, 5-year and 7-year survival rates were significantly different between the two groups (P <0.05). There was no significant difference in the 1-year and 3-year survival rates between the two groups (P> 0.05). Conclusion In vitro high-frequency hyperthermia treatment of advanced esophageal cancer long-term effect is satisfactory, the treatment is simple, less damage, safety protection, can improve the quality of life of patients.