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目的探讨重症肺部感染肾移植受者救治期间移植肾功能的保护。方法对15例肺部感染的肾移植患者的临床资料进行回顾性分析。结果15例重症肺部感染中有11例治愈,移植肾功能正常;死亡2例,放弃治疗2例。有12例检出病原菌,其中混合感染10例。结论重症肺部感染是肾移植术后的主要并发症,死亡率极高,早期诊断、及时调整免疫抑制剂方案以保护移植肾的功能和尽早确定病原菌等均有利于提高其抢救成功率。
Objective To investigate the protection of renal graft function in renal transplant recipients with severe pulmonary infection. Methods The clinical data of 15 patients with pulmonary infection were retrospectively analyzed. Results Of the 15 cases of severe pulmonary infection, 11 cases were cured, the function of renal graft was normal, 2 cases died and 2 cases were given up for treatment. Pathogenic bacteria were detected in 12 cases, including 10 cases of mixed infection. Conclusions Severe pulmonary infection is the main complication after renal transplantation. The mortality rate is extremely high. Early diagnosis and prompt adjustment of immunosuppressant regimen to protect the function of renal graft and to identify pathogenic bacteria as early as possible are beneficial to improve the success rate of rescue.