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近期对癌胚抗原的研究已超出肿瘤辅助诊断和预后判断的范围,向肿瘤发病机制及治疗等领域发展,现就此新动向进行综述。主要内容包括:癌胚抗原的分子结构、产生及清除;在结直肠癌发生与发展过程中的重要角色和作用机制;癌胚抗原靶向免疫治疗研究新进展等。
Recent research on carcinoembryonic antigen has gone beyond the scope of adjuvant diagnosis and prognosis of tumor, and has been developed in the field of tumor pathogenesis and treatment. Now we review the new trend. The main contents include: the molecular structure of carcinoembryonic antigen, production and removal of colorectal cancer in the occurrence and development of the important role and mechanism of action; carcinoembryonic antigen targeted immunotherapy research progress.