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目的:分析不典型川崎病发病情况,总结不典型川崎病诊断和治疗及早期使用IVIG对其预后的影响。方法:分析总结市妇幼保健院2011年1月~2013年12月收治的28例不典型川崎病患儿临床资料、实验室检查及心脏彩超对不典型川崎病的诊断价值。结果:(1)不典型川崎病不足典型川崎病6项临床表现中的5项,只有其中3~4项,除发热外,以口唇干红、双眼球结合膜充血较为常见,而颈淋巴结肿大及手足硬肿、指(趾)端脱皮出现率低。(2)早期应用静脉丙种球蛋白冠状动脉病变发生率低,预后好。结论:川崎病早期诊断、早期治疗可极大地减少冠状动脉病变的发生。
Objective: To analyze the incidence of atypical Kawasaki disease, summarize the impact of atypical Kawasaki disease diagnosis and treatment and early use of IVIG on its prognosis. Methods: The clinical data of 28 cases of atypical Kawasaki disease admitted to MCH hospital from January 2011 to December 2013 were analyzed. The diagnostic value of laboratory tests and echocardiography in patients with atypical Kawasaki disease was analyzed. Results: (1) Atypical Kawasaki disease is less than 5 of the 6 clinical manifestations of Kawasaki disease, only 3 to 4 of them. In addition to fever, lips dry red, binocular conjunctival hyperemia is more common, and cervical lymphadenopathy Large and hand, foot and sclerosis, finger (toe) side peeling rate is low. (2) The early application of intravenous gamma globulin coronary artery lesions is low, the prognosis is good. Conclusion: Kawasaki disease early diagnosis and early treatment can greatly reduce the occurrence of coronary artery disease.