目的　评价缬沙坦治疗轻中度高血压的降压疗效 ,对性功能的影响及安全性。方法　开放 ,多中心试验设计。对轻中度原发性高血压患者进行缬沙坦治疗前后血压水平、性功能指标的比较 ,并观察治疗中的不良反应。结果　缬沙坦治疗 8周后 ,坐位收缩压降低 19 5mmHg ,舒张压降低 13 9mmHg ,总有效率 86 9%。治疗后男女高血压患者性功能指标均有不同程度改善 ,尤以男性明显。 40岁以上中老年患者性功能指数升高更显著。治疗中无体位性低血压和严重不良事件发生。结论　缬沙坦降压疗效确切 ,不良反应少 ,可改善性功能 ,更适用于中老年高血压患者 Objective To evaluate the antihypertensive effect of valsartan on mild to moderate hypertension and its effect on sexual function and its safety. Methodology open, multicenter trial design. To mild to moderate essential hypertension in patients before and after valsartan treatment of blood pressure levels, sexual function comparison, and observe the treatment of adverse reactions. Results After valsartan treatment for 8 weeks, the systolic blood pressure decreased by 19 mmHg and the diastolic blood pressure decreased by 13.9 mmHg, with a total effective rate of 86.9%. After treatment, the male and female patients with hypertension have different degrees of sexual function improvement, especially in men. Sexual function index in elderly patients over the age of 40 increased more significantly. No orthostatic hypotension and serious adverse events occurred during treatment. Conclusion Valsartan antihypertensive effect is exact, less adverse reactions, can improve sexual function, more suitable for middle-aged and elderly hypertensive patients