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目的:应用镍钛记忆合金硅橡胶可复性输卵管栓进行动物实验研究,观察其抗生育效果和取栓后生育力恢复情况。方法:新西兰成年雌兔(实验组30只、对照组5只),经腹暴露子宫后,子宫近输卵管1cm处做一纵向0．5cm切口,将输卵管栓放入特制放置器顶端,顺序推出内部针芯、外部套管,使栓子留在输卵管内。术后1个月开始与雄兔合笼,每周交配1次(每月交配4次),观察避孕效果,术后3个月10只雌兔取出输卵管栓子观察可复性。结果:栓子放置术后2个月,30只雌兔中除1 只因栓子放置位置不当而妊娠外,其余29只均未妊娠。10只取出栓子后1个月内交配3次均妊娠。结论:镍钛记忆合金硅橡胶可复性输卵管避孕栓是一种新型、有效和可复性的输卵管避孕器具。
OBJECTIVE: To study the effect of anti-fertility and the restoration of fertility after the thrombectomy with NiTi Silicone Refractory Tubal Plug. Methods: New Zealand adult female rabbits (30 in experimental group and 5 in control group) were given a longitudinal 0.5cm incision at 1 cm proximal to the fallopian tube in the abdomen. The fallopian tubes were placed in the top of a special placer, Needle core, the outer casing, the emboli remain in the fallopian tubes. One month after surgery, the male rabbits were caged and mated once a week (4 times per month). The contraceptive effect was observed. Ten female rabbits were sacrificed to observe tubal embolus after 3 months. Results: Two months after the embolization, all but one of the 30 female rabbits were pregnant because of improper placement of the emboli. The remaining 29 women were not pregnant. 10 fetuses were removed within 3 months after mating three were pregnant. Conclusion: Nitinol silicone silicone recoverable tubal contraception is a new, effective and reproducible tubal contraceptives.