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目的:探讨血清中相关抗体检测在不孕不育分析中的临床意义。方法:以该院2014年10月至2015年10月收治的73例不孕不育患者为研究对象,将其作为观察组,另选取73例同一时期在我院进行健康体检者,将其作为对照组,采用增强的化学发光免疫分析法检测两组患者血清中的AoAb、AsAb、ACAb、EmAb。结果:观察组和对照组患者的ACAb、EmAb、AsAb及AoAb阳性率分别为2.74%、16.44%、21.92%、2.74%和0.00%、1.37%、0.00%、0.00%,观察组患者的ACAb、EmAb、AsAb及AoAb阳性率明显高于对照组患者(P<0.05)。观察组患者中,男、女性AsAb阳性率分别为13.33%(2/15)和24.14%(14/58),男性的AsAb阳性率明显低于女性(P<0.05)。结论:在不孕不育人群中,自身免疫抗体的阳性率较高。
Objective: To investigate the clinical significance of serum antibody in infertility analysis. Methods: A total of 73 inpatients with infertility treated in our hospital from October 2014 to October 2015 were selected as observation group and 73 healthy subjects were selected in our hospital during the same period. In the control group, serum AoAb, AsAb, ACAb and EmAb in two groups were detected by enhanced chemiluminescence immunoassay. Results: The positive rates of ACAb, EmAb, AsAb and AoAb in the observation and control groups were 2.74%, 16.44%, 21.92%, 2.74% and 0.00%, 1.37%, 0.00% and 0.00% The positive rates of EmAb, AsAb and AoAb were significantly higher than those in the control group (P <0.05). In the observation group, the positive rates of AsAb in male and female were 13.33% (2/15) and 24.14% (14/58) respectively. The positive rate of AsAb in male was significantly lower than that in female (P <0.05). Conclusion: In the infertility population, the autoimmune antibody positive rate is higher.