目的探讨血清降钙素原(PCT)对于小儿肺炎的临床诊断价值。方法从2014年6月~2016年6月期间在我院进行治疗的肺炎患儿中随机选取73例作为受试对象,按照患儿病原体感染情况进行分组,包括细菌性肺炎的患儿28例(甲组)、病毒性肺炎的患儿24例(乙组)及支原体肺炎的患儿21例(丙组)。其中细菌性肺炎患儿在治疗后有18例好转(好转组),10例未好转(未好转组)。将所有受试对象血清PCT的水平进行检测对比。结果细菌性感染的肺炎患儿PCT表达阳性率及表达水平均显著高于病毒性感染及支原体感染的肺炎患儿,且差异均有统计学意义(P<0.05);好转组患儿治疗后第四天及第七天的PCT水平均显著下降,未好转组患儿的PCT水平在治疗后第七天显著下降,差异均有统计学意义(P<0.05)。此外,好转组患儿在治疗后的PCT水平较未好转组患儿低,差异有统计学意义(P<0.05)。结论血清降钙素原在患有细菌性肺炎的患儿中的表达水平明显升高,且随着治疗后病情的逐渐缓解,血清降钙素原水平也逐渐下降,可以用于辅助肺炎患儿的临床诊断及对治疗效果进行评估。 Objective To investigate the value of serum procalcitonin (PCT) in the diagnosis of pneumonia in children. Methods A total of 73 children with pneumonia who were treated in our hospital from June 2014 to June 2016 were randomly selected as the subjects and were divided into groups according to the children’s pathogen infection. Among them, 28 cases were children with bacterial pneumonia Group A), 24 patients with viral pneumonia (Group B) and 21 patients with mycoplasmal pneumonia (Group C). In children with bacterial pneumonia after treatment in 18 cases improved (improved group), 10 cases did not improve (no improvement group). The level of serum PCT in all subjects was tested and compared. Results The positive rate and expression level of PCT in children with bacterial pneumonia were significantly higher than those in children with viral infection and mycoplasma pneumonia (P <0.05). After treatment, The levels of PCT decreased significantly on the four days and the seventh day, while the PCT levels in the untreated group decreased significantly on the seventh day after the treatment, with significant differences (P <0.05). In addition, the PCT level in the remission group was lower than that in the remission group (P <0.05). Conclusion The expression of procalcitonin in children with bacterial pneumonia increased significantly, and with the gradual alleviation of the disease after treatment, serum procalcitonin levels also gradually decreased, can be used to help children with pneumonia The clinical diagnosis and evaluation of the therapeutic effect.