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目的 :探讨新生儿胎粪吸入综合征 (MAS)的临床分型与治疗的关系。方法 :对 186例MAS患儿临床资料进行回顾性分析 ,根据临床症状、体征及辅助检查结果 ,将MAS患儿分为无症状型、普通型、急性呼吸窘迫综合征 (ARDS)型、肺动脉高压 (PPHN)型及肺出血型等 5种临床类型 ;根据病情严重程度分为轻型、重型和极重型等 3种临床类型。结果 :在 186例MAS患儿中 ,普通型、无症状型、PPHN型、肺出血型及ARDS型病例数分别为 133例 ( 71 5% )、2 8例 ( 15 1% )、13例 ( 7 0 % )、7例 ( 3 8% )及 5例 ( 2 7% ) ;轻型 10 9例 ( 58 6% )、重型 4 6例 ( 2 4 7% )和极重型 31例 ( 16 7% )。最后 ,158例 ( 84 9% )治愈 ,15例 ( 8 1% )好转 ,13例 ( 7 0 % )死亡。结论 :MAS的临床分型对于指导治疗和判断预后具有重要意义。
Objective: To investigate the relationship between clinical classification and treatment of neonatal meconium aspiration syndrome (MAS). Methods: The clinical data of 186 children with MAS were retrospectively analyzed. According to the clinical symptoms, signs and auxiliary examinations, children with MAS were divided into asymptomatic, common, acute respiratory distress syndrome (ARDS) type, pulmonary hypertension (PPHN) type and pulmonary hemorrhage and other five clinical types; according to the severity of the disease were divided into light, heavy and very heavy and other three types of clinical. Results: Among 186 children with MAS, the number of common type, asymptomatic type, PPHN type, pulmonary hemorrhage type and ARDS type were 133 cases (71.5%), 28 cases (15.1%) and 13 cases 70 cases (37%), 7 cases (38%) and 5 cases (27%); ). Finally, 158 (84.9%) were cured, 15 (81%) were cured and 13 (70%) were fatal. Conclusion: The clinical classification of MAS is of great importance for guiding treatment and prognosis.