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目的 :进一步了解氯氮平与其他抗精神病药物致白细胞减少的差异。方法 :按标准对收集的关于氯氮平与其他抗精神病药物致白细胞减少的对照研究论文作 Meta分析。结果 :(1)氯氮平与其他抗精神病药物导致白细胞减少存在着显著差异 (χ2 =7.2 5 7,P<0 .0 1) ;(2 )氯氮平引起白细胞减少的机率是其他抗精神药物的 1.49倍。结论 :氯氮平与其他抗精神病药物导致白细胞减少存在显著差异
Objectives: To further understand the differences in leukopenia caused by clozapine and other antipsychotics. METHODS: Meta-analysis of collected controlled-study articles on clozapine and other antipsychotics-induced leukopenia was conducted as standard. Results: (1) Clozapine and other antipsychotic drugs cause significant differences in leukopenia (χ2 = 7.25 7, P <0.01); (2) Clozapine caused leukopenia is the other anti-spirit 1.49 times the drug. CONCLUSIONS: Clozapine and other antipsychotics cause significant differences in leukopenia