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由药物副作用及不良反应引起的药源性疾病中以消化道损害为多见。本文分析35例药源性胃出血,以引起临床注意。 1 临床资料男24例,女11例,年龄18～72岁。致胃出血的口服药物有:复方阿斯匹林7例,去痛片11例,消炎痛8例,保泰松2例,炎通喜康2例,强的松2例,四环素2例,红霉素1例。空腹服药24例,餐后服药11例。有胃病史9例,无胃病史26例。服药后上腹隐痛11例,无自觉症状24例。服药致出血时间:<1天4例,～3天15例,～5天10例,～7天4例,>7天2例。出血前服药数量:最少3片,最多54片,5～30片占多数。1周内先后服用两种解热镇痛或抗炎药6例,伍用激素者2例,口服超常规剂量
Drug-induced side effects caused by adverse drug reactions and gastrointestinal damage is more common. This article analyzes 35 cases of drug-induced gastric bleeding, to cause clinical attention. 1 clinical data of 24 males and 11 females, aged 18 to 72 years. Oral drugs cause stomach bleeding: compound aspirin in 7 cases, to painkiller tablets in 11 cases, indomethacin in 8 cases, phenylbutazone in 2 cases, Yan Tong Xikang in 2 cases, prednisone in 2 cases, tetracycline in 2 cases, Erythromycin in 1 case. Fasting medication in 24 cases, 11 cases after taking medication. There are 9 cases of stomach history, no history of stomach disease in 26 cases. After taking abdominal pain in 11 cases, 24 cases without symptoms. Bleeding medication time: <1 day in 4 cases, ~ 3 days in 15 cases, ~ 5 days in 10 cases, ~ 7 days in 4 cases,> 7 days in 2 cases. The amount of medication before bleeding: at least 3, up to 54, 5 to 30 majority. One week after taking two antipyretic analgesic or anti-inflammatory drugs in 6 cases, 2 cases of hormone with hormone, oral super-conventional dose