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1998年5~6月,崇左县发生一起经流行病学、血清学和病毒学证实的麻疹流行。共报告316例病人,发病率为9638/10万。病例主要为学龄前儿童(109人)和中小学生(181人)。为查清本次麻疹暴发的原因,在该县非流行区按分层整群抽样的方法,抽取<1岁~≥30岁健康人322人,用酶联免疫吸附试验检测麻疹IgG抗体。结果抗体阳性率为6180%,几何平均滴度为1:32715,部分人群抗体达不到控制流行的水平。提示该县仍有发生麻疹流行的可能,应对14岁以下儿童普种MV,以形成免疫屏障。
From May to June 1998, a measles epidemic confirmed by epidemiology, serology and virology occurred in Chongzuo County. A total of 316 patients were reported with a prevalence of 9638 / 100,000. The main cases are preschool children (109) and primary and secondary students (181). In order to find out the cause of the measles outbreak, 322 healthy people aged from 1 to 30 years old were sampled in the non-endemic area of the county according to stratified cluster sampling. Measles IgG antibody was detected by enzyme-linked immunosorbent assay. Results The positive rate of antibody was 6180%, the geometric mean titer was 1: 32715, and some of the population did not reach the level of control prevalence. It is suggested that there is still a possibility that measles epidemic may occur in this county and universal MV should be dealt with in children under 14 to form immune barrier.