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[目的]探讨中医化积颗粒联合多酶片治疗小儿消化不良性腹泻的治疗效果及应用价值。[方法]选择我院治疗的小儿消化不良性腹泻患儿88例采取随机数字表法分为观察组和对照组,对照组给予多酶片治疗,观察组联合化积颗粒治疗,记录2组临床疗效。[结果]观察组临床治疗有效率为93.18%,显著优于对照组的75.00%(P<0.05)。观察组患儿大便次数恢复正常时间(2.41±1.11)d,退热时间(1.34±0.56)d,止吐时间(1.56±0.73)d,住院时间(8.38±1.86)d;对照组患儿大便次数恢复正常时间(3.87±1.87)d,退热时间(2.23±1.26)d,止吐时间(2.54±1.47)d,住院时间(12.23±2.94)d,组间比较差异有统计学意义(P<0.05)。治疗前2组血清胃泌素和P物质差异均无统计学意义(P>0.05),治疗后2组胃泌素和P物质均出现显著的升高(P<0.05和P<0.01),但观察组对胃泌素和P物质的升高作用显著优于对照组(P<0.05)。[结论]采用中医化积颗粒联合多酶片治疗小儿消化不良性腹泻临床疗效可靠,能够缩短住院时间和临床症状消失时间,调节患者胃肠激素分泌,值得在临床大力推广使用。
[Objective] To investigate the therapeutic effect and application value of traditional Chinese medicine combined with multi-enzyme tablets in the treatment of children with indigestion diarrhea. [Methods] 88 cases of children with dyspeptic diarrhea in our hospital were randomly divided into observation group and control group. The control group was treated with multi-enzyme tablets and the observation group was treated with combination of granulocyte-particles therapy. Two groups of clinical Efficacy. [Results] The effective rate of clinical treatment in the observation group was 93.18%, which was significantly better than that in the control group (75.00%, P <0.05). The stool frequency in observation group was 2.41 ± 1.11 days, the fever was 1.34 ± 0.56 days, the antiemetic time was 1.56 ± 0.73 days and the hospitalization time was 8.38 ± 1.86 days. (3.87 ± 1.87) d, antipyretic time (2.23 ± 1.26) d, antiemetic time (2.54 ± 1.47) d, and hospitalization time (12.23 ± 2.94) d respectively, there was significant difference between the two groups (P <0.05). There were no significant differences in serum gastrin and substance P between the two groups before treatment (P> 0.05). Gastrin and substance P were significantly increased in both groups after treatment (P <0.05 and P <0.01) The effect of gastrin and substance P in the observation group was significantly better than that of the control group (P <0.05). [Conclusion] The clinical effect of using traditional Chinese medicine combined with multi-enzyme tablets in the treatment of indigestion-induced diarrhea in children is reliable, which can shorten the length of hospitalization and disappearance of clinical symptoms and regulate the secretion of gastrointestinal hormones in patients, which is worth to be promoted and used clinically.