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枢复宁(又名Ondenstron及Zofran)是一种5-羟色胺_3(5-HT_3)受体拮抗剂,为新型有效控制恶心和呕吐的药物。大量临床资料表明,在癌瘤患者进行放、化疗过程中使用枢复宁能起到有效止吐作用,尤其与地塞米松合用对顺铂治疗引起严重恶心及呕吐的控制远较灭吐灵等药为佳。近来各国研究证实枢复宁对术后、尤其对麻醉后导致恶心及呕吐症状也起到良好的控制作用。因而1992年2月28日于伦敦召开枢复宁在控制术后恶心及呕吐的国际会议,通称
Chuan Fu Ning (also known as Ondenstron and Zofran) is a serotonin-3 (5-HT3) receptor antagonist and is a novel and effective drug for controlling nausea and vomiting. A large number of clinical data have shown that the use of shufuning can play an effective antiemetic effect in the course of radiotherapy and chemotherapy for cancer patients, especially in combination with dexamethasone. Control of severe nausea and vomiting caused by cisplatin treatment is much better than that of extermination and so on. The medicine is better. Recent studies in various countries have confirmed that it has a good control of postoperative nausea and vomiting, especially after anesthesia. Therefore, an international conference on controlling postoperative nausea and vomiting was held in London on February 28, 1992.