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巨噬细胞浸润的程度与肾功能的丧失和组织学的损害密切相关,是预测肾脏疾病转归的重要指标之一[1]。Fractalkine是趋化因子CX3C亚家族的惟一成员[2],其受体CX3CR1主要表达在单核巨噬细胞、T细胞和NK细胞上[3],介导fractalkine表达细胞对上述细胞的趋化作用。本研究意在观察
The extent of macrophage infiltration is closely related to the loss of renal function and histological damage, and it is one of the important indexes to predict the outcome of renal disease [1]. Fractalkine is the only member of chemokine CX3C subfamily [2]. Its receptor CX3CR1 is mainly expressed on monocytes, T cells and NK cells [3], which mediates chemotaxis of fractalkine-expressing cells to these cells . This study is intended to observe