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建立了用表达Epstein-Bar病毒壳抗原gp125的重组痘苗病毒感染细胞为抗原,检测IgA/gp125抗体的免疫酶法,并检测了鼻咽癌、其它肿瘤病人和正常人的IgA/gp125抗体,其灵敏度远远高于IgA/EA,接近于IgA/MA和IgA/VCA,特异性高于IgA/MA和IgA/VCA,接近于IgA/EA。
A recombinant vaccinia virus expressing Epstein-Bar virus shell antigen gp125 was used as an antigen to detect IgA / gp125 antibody by immunoenzymatic assay. IgA / gp125 antibody was detected in nasopharyngeal carcinoma, other tumor patients and normal individuals Sensitivity is much higher than IgA / EA, close to IgA / MA and IgA / VCA, specificity is higher than IgA / MA and IgA / VCA, close to IgA / EA.