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目的:比较M型超声心动图(M-mode echocardiography,MME)、二维超声心动图(two-dimensional echocardiography,2DE)、实时三维超声心动图(real-time three-dimensional echocardiography,RT-3DE)定量评价健康志愿者左心室收缩功能(left ventricular systolic function,LVSF)指标的测值大小、相关性和可重复性。方法:分别采用MME的Teichholz公式法、2DE的双平面Simpson法、RT-3DE测量31名健康志愿者左室射血分数(left ventricular ejection fraction,LVEF)和每搏量(stroke volume,SV),并比较3种方法的测值大小、相关性和可重复性。结果:(1)MME、2DE、RT-3DE测得的射血分数(ejection fraction,EF)分别是(67.50±3.38)%、(66±3.31)%、(60.11±3.40)%,SV分别是(69.46±14.90)m L、(65.58±12.40)m L、(59.29±12.31)m L,差异均有统计学意义(P<0.05),EF、SV均呈递减趋势,即MME测值最大,RT-3DE测值最小;(2)3种方法测定的EF和SV相关性均好,其中MME与2DE、RT-3DE测得的EF相关系数分别为0.802、0.933;2DE与RT-3DE测得的EF相关系数为0.822;MME与2DE、RT-3DE测得的SV相关系数分别为0.901、0.689;2DE与RT-3DE测得的SV相关系数为0.735;(3)Bland-Altman图显示同1测试者前后及不同测试者之间测值均有较好的重复性。结论:3种方法均能正确评价正常健康者的LVSF,且相关性和重复性均好,其中MME测得EF和SV相对偏高,RT-3DE测得EF和SV相对偏低。
Objective: To compare the effects of M-mode echocardiography (MME), two-dimensional echocardiography (2DE) and real-time three-dimensional echocardiography To evaluate the size, correlation and repeatability of left ventricular systolic function (LVSF) in healthy volunteers. Methods: Left ventricular ejection fraction (LVEF) and stroke volume (SV) were measured in 31 healthy volunteers using MME’s Teichholz’s formula method, 2DE’s biplane Simpson’s method and RT-3DE respectively. The measured values, correlation and repeatability of the three methods were compared. Results: (1) The ejection fraction (EF) measured by MME, 2DE and RT-3DE were (67.50 ± 3.38)%, (66 ± 3.31)% and (60.11 ± 3.40)%, respectively (69.46 ± 14.90) m L, (65.58 ± 12.40) m L and (59.29 ± 12.31) m L, respectively, with statistical significance (P <0.05). EF and SV showed a decreasing trend. RT-3DE measured the minimum; (2) The correlation between EF and SV measured by the three methods are good, which MME and 2DE, RT-3DE measured EF correlation coefficients were 0.802,0.933; 2DE and RT-3DE measured EF was 0.822; SV correlation coefficient between MME and 2DE and RT-3DE was 0.901 and 0.689 respectively; correlation coefficient of SV between 2DE and RT-3DE was 0.735; (3) Bland-Altman graph showed the same correlation coefficient Before and after the test and test between different testers have better repeatability. CONCLUSION: All three methods can correctly evaluate the LVSF of normal healthy people, and the relativity and repeatability are good. MME and EF have higher relative EF and SV, and relatively lower EF and SV measured by RT-3DE.