中药调脂合剂联合辛伐他汀治疗高血脂症随机对照临床研究

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[目的]观察中药调脂合剂联合辛伐他汀治疗高血脂症的临床疗效。[方法]回顾性分析我院收治的140例高血脂症患者的临床资料,随机分为治疗组70例和对照组70例。对照组服用辛伐他汀胶囊,1次/d,20mg/次,治疗组在对照组治疗基础上服用中药调脂合剂(药用大黄、姜黄、水蛭、黄精、陈皮,等),60d为1疗程。治疗1个疗程后判定疗效。[结果]两组各项指标均有显著改善(P<0.05);同时治疗组TG、TC等指标的改善情况显著优于对照组(P<0.05);治疗组总有效率97.14%,对照组总有效率71.43%,治疗组优于对照组(P<0.05)。[结论]中药调脂合剂联合辛伐他汀治疗高脂血症,效果显著,优于单纯西医治疗。 [Objective] To observe the clinical efficacy of traditional Chinese medicine Tiaozhi Mixture and Simvastatin in the treatment of hyperlipidemia. [Methods] The clinical data of 140 cases of hyperlipidemia admitted to our hospital were retrospectively analyzed. They were randomly divided into treatment group (70 cases) and control group (70 cases). The control group took simvastatin capsules once a day, 20mg once daily. The treatment group took the traditional Chinese medicine balm (medicinal rhubarb, turmeric, leech, polygonatum, dried tangerine peel, etc.) on the basis of the control group for 60 days for one course of treatment . Treatment of a course of treatment to determine the efficacy. [Results] The indexes of both groups were significantly improved (P <0.05). At the same time, the improvement of TG, TC and other indexes in the treatment group was significantly better than that in the control group (P <0.05). The total effective rate in the treatment group was 97.14% The total effective rate was 71.43%, the treatment group was better than the control group (P <0.05). [Conclusion] Tiaozhi Mixture combined with Simvastatin in treating hyperlipidemia has a significant effect, which is better than that of Western medicine alone.
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