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目的:探索医学生对医学职业精神的认知水平及其影响因素。方法:采用问卷调查方法。选取天津医科大学2016～2021级五年制和“5＋3”一体化临床医学专业及四年制护理学专业本科生为研究对象，采用简体中文版医学生职业精神认知水平自评问卷，在2020年新型冠状病毒肺炎疫情防控的2个不同阶段(抗击新冠肺炎疫情第四阶段和全国疫情防控进入常态化)开展2次调查，通过Mann-Whitneyn U秩和检验、多元线性回归分析等方法进行数据分析。n 结果:分别有860名医学生和693名医学生参与了2次调查，医学生对医学职业精神认知水平评分分别为[4.7(0.9)分]和[4.6(0.8)分]；专业满意度越高的医学生的医学职业精神的认知水平越高(n b＝0.225，n P<0.001)；与低年级医学生相比，高年级医学生对医学职业精神的认知水平较低(n b＝－0.147，n P<0.001)。2次调查均参与的375名医学生对医学职业精神认知水平评分比较，第二次评分[4.5(0.9)分]低于第一次[4.7(0.9)分](n P<0.001)。n 结论:医学生对医学职业精神的认知水平总体较高；医学生的专业满意度和所在年级是其医学职业精神认知水平的影响因素，应当继续发挥“抗疫精神”对医学生职业精神的培育作用。“,”Objective:To explore the perceptions of medical students to medical professionalism and its influencing factors.Methods:Questionnaires were conducted. Undergraduate students majoring in five-year program, 5+ 3 integrated clinical medicine, and four-year nursing program in Tianjin Medical University from 2016 to 2021 were selected as subjects. The Simplified Chinese Version Self-assessment tool was adopted to measure student\'s perception of medical professionalism (the SCV-SPMP ). Two surveys were conducted at two different stages of COVID-19 prevention and control in 2020 (phase IV of COVID-19 prevention and control and normalization of COVID-19 prevention and control nationwide). The data were analyzed by Mann-Whitneyn U rank sum test, multiple linear regression analysis.n Results:There were 860 students and 693 students participated in two questionnaires respectively, the total score of medical student\'s perceptions to medical professionalism were [4.7 (0.9)] and [4.6 (0.8)] respectively. The more satisfied from their major, the more are positive to their perception of medical professionalism (n b=0.225, n P<0.001). Senior medical students’ perception on medical professionalism is lower than those of junior medical students (n b=-0.147, n P<0.001). Comparing the scores of 375 medical students who participated in both surveys , the total score of the first questionnaire [4.5(0.9)] was higher than that of the second questionnaire [4.7(0.9)] (n z=-4.42, n P<0.001).n Conclusions:Medical students\' perception to medical professionalism is generally at a high level. Their satisfaction from the major choice and education experience in the medical school are the factors that affect medical students\' perception of medical professionalism. COVID-19 pandemic has an impact on medical students\' perceptions of medical professionalism.