【摘 要】
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Shensong Yangxin (SSYX) is one of the compound recipes of Chinese materia medica including 12ingredients such as Panax ginseng, dwarf lilyturf tuber,nardostachy
【机 构】
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Pathology and Physiology Research Center,Yiling Pharmaceutical Corporation
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Shensong Yangxin (SSYX) is one of the compound recipes of Chinese materia medica including 12ingredients such as Panax ginseng, dwarf lilyturf tuber,nardostachys root, etc. Small-scale randomized multi-centre clinical trials suggested that SSYX reduced the number of ventricular extrasystoles in patients with or without structural heart disease.1 Besides excellent antiarrhythmic efficacy,2 SSYX also improved bradycardia in some patients, which was evidenced by animal studies3 as well. However, the antiarrhythmic mechanisms of SSYX have not been fully understood.Our previous studies have explored effect of SSYX on many channels except hyperpolarization-activated cation channel encoded by human hHCN4 gene.4
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