目前对早产儿的诊断尚缺乏理想的检查方法,本文对17例严重持续肺功能衰竭患儿的开胸肺活检作了回顾性分析,旨在探讨此法对危重新生儿诊断和治疗的临床意义.方法本组17例患儿,其母妊娠周期为25～33周,患儿出生体重570～3030g,肺活检时年龄13～242日,活检时体重700～5000g,活检部位根据胸片提示选择最为可疑的病变处。全部病例采用静脉和局部麻醉,通过前侧开胸取出一小块肺组织,作需氧菌、 At present, the diagnosis of premature infants is still lack of an ideal examination method. In this paper, 17 cases of severe persistent pulmonary failure in children with open lung biopsy were analyzed retrospectively to explore the clinical significance of this method for diagnosis and treatment of critically ill newborns .Methods The group of 17 children with pregnancy of 25 ~ 33 weeks, birth weight 570 ~ 3030g, lung biopsy age 13 ~ 242 days, biopsy weight 700 ~ 5000g, the biopsy site based on the prompt selection The most suspicious lesions. All cases were treated with intravenous and local anesthesia, a small piece of lung tissue was removed through the anterior thoracotomy for aerobic bacteria,