The influence of external noise on intracellular Ca2+ oscillations dynamics in a single cell of rat hepatocytes is studied.The coherence of noise-induced intracellular Ca2+ oscillations reached two maxima for multiple external noise intensity, indicating the occurrence of external noise stochastic bi-resonance (SBR).This phenomenon is compared with our previous result that was induced by internal noise.Additionally, the deterministic bifurcation character of the system was also discussed.