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目的了解居家化疗传染性肺结核患者服药依从性状况,探讨其可能的影响因素。方法采用分层随机抽样方法,选取山东省6个地区共720例居家化疗肺结核患者作为研究对象,使用自行编制的问卷对其进行调查。结果 720例调查对象中,男性506例(70.3%),女性214例(19.7%);服药依从者316例(43.9%),服药不依从者404例(56.1%);未婚118例(16.4%),已婚551例(76.5%),离婚或丧偶50例(6.9%),以离婚或丧偶作为参照,在婚者服药依从性较好(OR=0.490,P=0.026);新农合621例(86.2%),城镇职工医保99例(13.8%),以新农合为参照,城镇职工医保患者服药依从性较差(OR=2.415,P=0.003);城镇户籍56例(7.8%),农村户籍664例(97.2%),以城镇户籍为参照,农村户籍患者服药依从性较差(OR=2.019,P=0.044)。结论山东6县区居家化疗传染性肺结核患者半数以上存在服药不依从行为,服药依从性与婚姻状态、医疗保障类型以及家庭户籍类型相关。
Objective To understand the medication adherence status of patients with communicable pulmonary tuberculosis in home chemotherapy and to explore the possible influencing factors. Methods A stratified random sampling method was used to select 720 cases of home-based chemotherapy pulmonary tuberculosis in 6 districts of Shandong Province as the research object, and the questionnaires were used to investigate. Results Among the 720 surveyed subjects, 506 (70.3%) were male and 214 (19.7%) were female; 316 (43.9%) were drug dependent and 404 (56.1% ), Married 551 (76.5%), divorced or widowed 50 (6.9%), divorced or widowed as a reference, married drug users compliance is better (OR = 0.490, P = 0.026); NRCMC 621 (86.2%), and 99 workers (13.8%) in cities and towns were covered by medical insurance. According to the NRCMS, the medical insurance for urban employees was less compliant (OR = 2.415, P = 0.003) 664 cases of rural household registration (97.2%), taking urban household registration as a reference, poor compliance of rural household registration (OR = 2.019, P = 0.044). Conclusion More than half of inpatients with tuberculosis in villages in 6 counties of Shandong Province are not compliance with medication taking. Drug compliance is related to marital status, type of medical insurance and type of household registration.