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目的探讨热习服干预对海训官兵血浆胃肠激素和免疫状况的影响。方法 125名在东南沿海某地进行夏季海训官兵随机分为热习服干预组和对照组。在海训前对热习服组60名官兵进行人工热间和室外着雨衣热习服干预12d,随后两组官兵均执行为期2个月的海训任务;放射免疫法检测海训前后血浆胃动素(MTL)、血管活性肠肽(VIP)和生长抑素(SS)水平,流式细胞仪检测海训前后外周血T、B、NK淋巴细胞亚群的变化。结果热习服干预组官兵海训前后血浆MTL、VIP和SS水平差异无统计学意义(P>0.05),而对照组官兵海训后血清MTL较海训前明显增高,VIP和SS水平显著降低(P<0.05);海训后热习服干预组官兵CD3+、CD3+CD4+、淋巴细胞和CD4+/CD8+均明显高于对照组(P<0.05),CD3+CD8+和CD3-CD56+均明显低于对照组(P<0.05)。结论适当热习服干预能提高海训官兵胃肠功能稳定性和细胞免疫功能。
Objective To investigate the effects of heat intervened on plasma and gastrointestinal hormones and immune status in sea training officers and soldiers. Methods Totally 125 summer sea training officers and men in a southeastern coastal area were randomly divided into heat-acclimation intervention group and control group. Before the sea training, 60 officers and men in the heat-acclimatization group were intervened for 12 days by manual hot weather and outdoor raincoats, followed by two months of sea training missions by both officers and men. Radioimmunoassay (MTL), vasoactive intestinal peptide (VIP) and somatostatin (SS). The changes of T, B and NK lymphocyte subsets in peripheral blood before and after training were detected by flow cytometry. Results There was no significant difference in the levels of MTL, VIP and SS before and after heat training intervention group (P> 0.05), while the serum MTL in the control group was significantly higher than that before training, and the VIP and SS levels were significantly lower (P <0.05). After training, the CD3 +, CD3 +, CD4 +, CD4 + / CD8 + and CD3 + CD8 + CD3 + Control group (P <0.05). Conclusion Intervention with appropriate heat can increase the gastrointestinal function stability and cellular immune function of sea training officers and soldiers.