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中东呼吸综合征(middle eastern respiratory syndrome,MERS)是由中东呼吸综合征冠状病毒(MERS-CoV)引起的呼吸道疾病,严重者可发生急性呼吸窘迫综合征、急性肾功能衰竭,甚至多脏器功能衰竭。该病自2012年首次报告以来,截至2017年7月28日,共有27个国家和地区报告了确诊病例2 040例,其中死亡病例712例,病死率34.90%,对全球公共卫生构成重大威胁。本文从MERS的疫情概况、病原学、传播方式以及防治措施4个方面进行综述,以期为有效预防和控制该病提供参考。
Middle eastern respiratory syndrome (MERS) is a respiratory disease caused by the Middle East respiratory syndrome coronavirus (MERS-CoV). In severe cases, acute respiratory distress syndrome, acute renal failure and even multiple organ dysfunction may occur Failure. Since its first report in 2012, as of July 28, 2017, a total of 2 040 confirmed cases were reported in 27 countries, including 712 fatal cases and a case fatality rate of 34.90%, posing a significant threat to global public health. This article reviews the general situation of MERS, etiology, mode of transmission and prevention and treatment measures in order to provide reference for effective prevention and control of the disease.