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报告20例食管小细胞癌,其中19例与5例低分化鳞癌同时作免疫组织化学研究,有7例食管小细胞癌与低分化鳞癌一致,只表达上皮性质,提示了食管小细胞癌可能不都是起源于APUD系细胞,而是一组不同起源的分化极差的恶性肿瘤。由于病理根据细胞形态可作出诊断,及时采用综合治疗措施将更加有效。
20 cases of small cell carcinoma of the esophagus were reported, of which 19 cases and 5 cases of poorly differentiated squamous carcinoma were studied simultaneously by immunohistochemistry. 7 cases of esophageal small cell carcinoma were consistent with poorly differentiated squamous cell carcinoma. They only expressed epithelial nature, suggesting small cell carcinoma of the esophagus. It may not all originate from the APUD lineage but is a group of malignancies of very different differentiation from different origins. Since the pathology can be diagnosed based on the cell morphology, the timely adoption of comprehensive treatment measures will be more effective.