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骨髓移植后组织学分析提供结构和基质以及造血重建的信息.这些对认识不完全嵌合、移植排异和白血病复发等同题是重要的.本文对24例急粒、3例急淋的44个移植后骨髓;9例严重再障移植后17个骨髓进行分析.移植当天取到的8个标本表现重度细胞消减(<30%),多数细胞为成熟粒细胞、肥大细胞、浆细胞、淋巴细胞和巨噬细胞,还有PAS(+)的脂肪细胞和纤维母细胞样细胞,其中6例有水肿,网硬蛋白在3例再障中1例中度增加,5例白血病中3例轻度增加,2例中度到显著增加.
Histological analysis of bone marrow transplantation provides information on the structure and matrix and on hematopoietic reconstitution, which are important for recognizing incomplete chimerism, rejection of transplant and relapse of leukemia, etc. In this paper, 24 acute and 3 acute lymphocytic Seventeen bone marrow samples from 9 severely impaired allografts were analyzed.The eight specimens collected on the day of transplantation showed severe cytoreduction (<30%), most of them were mature granulocytes, mast cells, plasma cells and lymph Cells and macrophages, as well as PAS (+) adipocytes and fibroblast-like cells, with edema in 6 of them, moderate increase of reticulum protein in 1 of 3 patients with aplasia, and 3 of 5 leukemia Degree increased, 2 cases moderate to significant increase.