目的:观察短效与长效硝苯地平治疗妊娠高血压的临床效果。方法:选取我院收治的妊娠高血压患者780例,按照分层随机法分成长效组和短效组,两组患者均采取硫酸镁治疗,长效组加用长效硝苯地平治疗,短效组加用短效硝苯地平治疗,比较两组临床效果。结果:长效组治疗后平均收缩压、平均舒张压均好于短效组,差异有统计学意义(P<0.05)。长效组顺产率明显高于短效组,差异有统计学意义(P<0.05)。长效组宫内窘迫率、围生儿死亡率均低于短效组,差异有统计学意义(P<0.05)。结论:长效硝苯地平片疗效较之普通硝苯地平片更好,并能长期维持,可在妊娠高血压的治疗中联合硫酸镁使用。 Objective: To observe the clinical efficacy of short-acting and long-acting nifedipine in the treatment of pregnancy-induced hypertension. Methods: 780 cases of pregnancy-induced hypertension admitted to our hospital were divided into long-acting group and short-acting group according to the stratified randomized method. Both groups were treated with magnesium sulfate and long-acting group with long-acting nifedipine Effective group plus short-acting nifedipine treatment, the clinical effects of two groups were compared. Results: The average systolic blood pressure and average diastolic blood pressure in the long-acting group were better than those in the short-acting group after treatment. The difference was statistically significant (P <0.05). The long-acting group cis-production rate was significantly higher than the short-acting group, the difference was statistically significant (P <0.05). Long-effect group of intrauterine distress rate, perinatal mortality were lower than the short-term group, the difference was statistically significant (P <0.05). CONCLUSION: The long-acting nifedipine tablet has better curative effect than ordinary nifedipine tablet and long-term maintenance. It can be used together with magnesium sulfate in the treatment of pregnancy-induced hypertension.