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作者共检查了190例红斑狼疮的免疫功能,其中盘状126例、系统性50例、过渡型14例。盘状红斑狼疮92.1%病例T系统免疫缺陷,表现为淋巴细胞相对和绝对计数中度降低——相应为42±12%(正常60±7%)和945±30个/立方毫米(正常1100±25个/立方毫米),对PHA的淋巴细胞转化率42±11%(正常56±8%),对DNA的淋巴细胞转化率下降——18±5%。87.3%病例对DNA有淋巴细胞移动抑制因子,为24±3单位(正常43±6单位)。以皮内试验以及对靶细胞作用可见盘状红斑狼疮有T淋巴细胞的细胞毒性。B系统免疫机能无亢进。所有慢性和亚急性病程的系统性红斑狼疮T淋
The authors examined 190 cases of lupus erythematosus immune function, of which 126 cases of disc, the system of 50 cases, 14 cases of transitional. In 92.1% of cases of Discoid Lupus Erythematosus, T-system immunodeficiency manifested as a modest decrease in relative and absolute lymphocyte counts - 42 ± 12% (normal 60 ± 7%) and 945 ± 30 / mm3 (normal 1100 ± 25 per cubic millimeter), lymphocyte conversion to PHA 42 ± 11% (normal 56 ± 8%), and DNA conversion to lymphocytes down -18 ± 5%. 87.3% of cases had lymphocyte migration inhibitory factor for DNA, 24 ± 3 units (normal 43 ± 6 units). To intradermal test and the role of target cells visible discoid lupus erythematosus T lymphocyte cytotoxicity. B system immune function without hyperthyroidism. All chronic and subacute systemic lupus erythematosus T lymph nodes