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目的探讨脾氨肽辅助治疗儿童过敏性咳嗽的临床疗效。方法将2011年3月至2012年7月在我院门诊就诊的过敏性咳嗽的患儿80例随机分为两组,两组病例均使用吸入糖皮质激素,观察组在对照组治疗基础上给予口服脾氨肽,比较治疗后两组疗效。结果观察组总有效率同对照组比较有显著性差异(P<0.01)。治疗前后血免疫球蛋白检测的变化有明显差异。结论使用脾氨肽辅助治疗儿童过敏性咳嗽疗效肯定,无明显不良反应,临床上可考虑使用。
Objective To investigate the clinical efficacy of splenic aminopeptidase in the treatment of allergic cough in children. Methods Eighty children with allergic cough from March 2011 to July 2012 in our hospital were randomly divided into two groups. Patients in both groups were given inhaled corticosteroids. The observation group was given on the basis of the treatment of the control group Oral spleen aminopeptid, compared two groups after treatment efficacy. Results The total effective rate of the observation group compared with the control group were significantly different (P <0.01). Changes in blood immunoglobulin test before and after treatment were significantly different. Conclusions The use of splenic aminopeptidate adjuvant treatment of children with allergic cough certainly effect, no obvious adverse reactions, can be considered for clinical use.