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多发性骨髓瘤(MM)是浆细胞异常增殖疾病,表现为骨痛、病理性骨折、肾功能损害,常易导致误诊。我们曾遇2例,报告如下。 例1:男,36岁。因腰痛2个月就诊。化验尿常规尿蛋白(++),有管型,白细胞(++),Hb86g/L,WBC5.6×10~9/L。诊断为慢性肾炎。经治疗半年未见好转,并出现T_8病理骨折。骨髓穿刺示病理性浆细胞0.88。颅骨、骨盆X线片示大量虫蚀样病变,即诊为MM,用M_2方案化疗2个疗程完全缓解。 例2:男,45岁。因腰痛伴发热半年,按椎间盘脱出治疗无好转就诊。体检:贫血貌,胸骨压病,腰3、4椎体压痛。化验
Multiple myeloma (MM) is an abnormal proliferation of plasma cells disease, manifested as bone pain, pathological fractures, renal dysfunction, often lead to misdiagnosis. We have encountered two cases, the report is as follows. Example 1: Male, 36 years old. Due to low back pain 2 months treatment. Laboratory urinalysis urine protein (+ +), tubular, white blood cells (++), Hb86g / L, WBC5.6 × 10 ~ 9 / L. Diagnosis of chronic nephritis. After six months of treatment did not improve, and T_8 pathological fracture. Bone marrow aspirate showed pathological plasma cells 0.88. Skull, pelvis X-ray showed a large number of worm-like lesions, the diagnosis of MM, with M 2 regimen of 2 courses of complete remission of chemotherapy. Example 2: Male, 45 years old. Due to low back pain with fever for six months, press disc herniation without improvement treatment. Physical examination: anemia appearance, sternal pressure disease, lumbar 3,4 vertebral tenderness. assay