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哺乳动物的烯醇化酶是由α、β、γ三种免疫学上截然不同的亚单位组成的二聚体。β—烯醇酶(αβ和ββ型)主要存在于心肌和骨骼肌中。晚期kato 等利用灵敏的免疫学测定证实,血清β—烯醇酶对人类肌性疾病的诊断是一项有价值的指标。作者用各种心血管疾病患者的血清测定β—烯醇酶浓度以确定此酶对急性心肌梗塞的诊断是否有帮助。受试者包括(1)26例首发急性心肌梗塞的住院病人(年龄38—84岁,男21,女5例),均无神经肌肉性病变。(2)10例心绞疼病人(年龄36—61岁,均为男性)。其中8例并发充血性心衰(非
Mammalian enolase is a dimer composed of three immunologically distinct subunits of α, β, γ. [beta] -enolases ([alpha] [beta] and [beta] [beta] forms) are predominantly found in cardiac and skeletal muscle. Late kato and other sensitive immunological assays confirmed that the serum β-enolase diagnosis of human muscle disease is a valuable indicator. The authors determined β-enolase concentrations in sera of patients with various cardiovascular diseases to determine if this enzyme might be helpful in the diagnosis of acute myocardial infarction. Subjects included (1) 26 patients with first-episode acute myocardial infarction (38-84 years of age, 21 males and 5 females) with no neuromuscular lesions. (2) 10 cases of angina patients (age 36-61 years, all men). 8 cases of congestive heart failure (non