论文部分内容阅读
近年来临床内分泌学进展很快,其主要原因是内分泌测定技术特别是放射免疫测定法(RIA)有了很大发展。1959年Berson.Yalow氏首先用放射线同位素标记胰岛素抗原与胰岛素特异抗体进行免疫反应来测定胰岛素的含量。此法灵敏度高,特异性强,很引人重视。其后相继应用于各种蛋白质多肽激素(促黄体生成素LH、促卵泡生成素FSH、绒毛膜促性腺激素HCG、促肾上腺皮质激素ACTH等)的血中微量测定。最近已用于测定低分子的固醇类激素(雌激素、孕激素、付肾皮质激素),丘脑下部激素,垂体后叶
In recent years, clinical endocrinology progresses rapidly, the main reason is that endocrine assay technology, especially radioimmunoassay (RIA) has made great progress. 1959 Berson .Yalow’s first determination of insulin content by radioactive isotope labeled insulin antigen and insulin-specific antibodies. This method is highly sensitive, specific, very attractive. Subsequent application of a variety of protein peptide hormones (luteinizing hormone LH, follicle stimulating hormone FSH, human chorionic gonadotropin HCG, adrenocorticotrophic hormone ACTH, etc.) blood micro-determination. Recently, it has been used to determine low molecular weight steroid hormones (estrogen, progestin, corticosteroid), hypothalamic hormone, posterior pituitary