目前,经皮腔内冠状动脉成形术和冠状动脉内支架置入术已广泛应用于临床,成为冠心病常规介入治疗的方法之一,但术后再狭窄率仍然居高不下;药物洗脱支架的出现则改变了这种局面,随着近两年来药物洗脱支架防治再狭窄临床实验结果的陆续公布,使药物洗脱支架成为目前防治再狭窄的最佳办法。现根据医学研究的最新结果,从药物洗脱支架的作用机制、临床疗效和安全性等方面作一综述。 Currently, percutaneous transluminal coronary angioplasty and coronary stenting have been widely used in clinical practice, becoming one of the routine interventional treatment of coronary heart disease, but the rate of postoperative restenosis remains high; drug-eluting stent The emergence of this situation has changed, with the recent two years of drug-eluting stent prevention and treatment of restenosis clinical trial results announced one after another, the drug-eluting stent as the best way to prevent restenosis. According to the latest results of medical research, the mechanism, clinical efficacy and safety of drug-eluting stents are reviewed.